T41B + BD10-2 + stim
View on GitHub Counts dashboard DE dashboard Stimulation dashboard
- Model: T41B
- Age: 16 month
- Drug: BD10-2
- Treatment: LTP
- Tissue: Hippocampus
- Time since last dose: 24h
- RNA-seq type: Bulk
Table of contents
Publications
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer’s mouse model Amira Latif-Hernandez, Tao Yang, Robert Raymond Butler III, Patricia Moran Losada, Paras S Minhas, Halle White, Kevin Chan Tran, Harry Liu, Danielle Simmons, Vanessa Langness, Katrin Andreasson, Tony Wyss-Coray, Frank M Longo Alzheimer’s & Dementia 20(7)4434-4460.
Methods
Code for analysis where available is in the github link above. Additional information regarding settings for trimming, mapping and differential expression are available on request.