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Plasma Biomarker Proteomics

View on GitHub WSSmod

  • Cohort: Stanford ADRC
  • Species: Human
  • Sample type: Plasma
  • Assay: Proteomics
  • Analysis: WSSmod weighted module scoring

Table of contents

Publications

Butler RR 3rd, Brown MP, Weber A, Cary GA, Le Guen Y, Moran Losada P, Mendiola JH, Henderson VW, Sha SJ, Poston KL, Andreasson KI, Wagner AD, Mormino EC, Wyss-Coray T, Longo FM, Wilson EN. Alzheimer’s disease blood biomarkers reveal proteomic modules of disease progression. medRxiv 2026.08.14.26360394. https://doi.org/10.64898/2026.08.14.26360394

Methods

Analysis code is available in the GitHub repos linked above: Plasma_Ptau_Proteomics for the primary proteomics analysis, and WSSmod for the weighted module scoring package used to summarize protein network modules into biomarker scores.